Review



rat bdnf elisa kits  (Boster Bio)


Bioz Verified Symbol Boster Bio is a verified supplier
Bioz Manufacturer Symbol Boster Bio manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 93

    Structured Review

    Boster Bio rat bdnf elisa kits
    Experimental Timeline: Rats were treated with EE, RJ, and EE + RJ for 14 consecutive days. Stress was induced on days 8–14. Behavioral tests were conducted on days 15–18. On day 19, the animals were decapitated to assess serum corticosterone and hippocampal <t>BDNF</t> levels.
    Rat Bdnf Elisa Kits, supplied by Boster Bio, used in various techniques. Bioz Stars score: 93/100, based on 17 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rat+bdnf+elisa+kits/Rat+BDNF+ELISA+Kit+EZ-Set/pmc13092850-95-33-38
    Average 93 stars, based on 17 article reviews
    rat bdnf elisa kits - by Bioz Stars, 2026-09
    93/100 stars

    Images

    1) Product Images from "Pre-treatment with royal jelly, environmental enrichment, and their combination role in stress induced neurobehavioral deficits in male rats"

    Article Title: Pre-treatment with royal jelly, environmental enrichment, and their combination role in stress induced neurobehavioral deficits in male rats

    Journal: IBRO Neuroscience Reports

    doi: 10.1016/j.ibneur.2026.03.012

    Experimental Timeline: Rats were treated with EE, RJ, and EE + RJ for 14 consecutive days. Stress was induced on days 8–14. Behavioral tests were conducted on days 15–18. On day 19, the animals were decapitated to assess serum corticosterone and hippocampal BDNF levels.
    Figure Legend Snippet: Experimental Timeline: Rats were treated with EE, RJ, and EE + RJ for 14 consecutive days. Stress was induced on days 8–14. Behavioral tests were conducted on days 15–18. On day 19, the animals were decapitated to assess serum corticosterone and hippocampal BDNF levels.

    Techniques Used:

    The effects of EE and RJ treatment on the hippocampal BDNF expression. The BDNF levels in the stressed group were significantly decreased than in the control group. EE and RJ treatment increased BDNF levels in the stressed rats. *, **, and *** represent p < 0.05, p < 0.01, and p < 0.001 v.s. the Non-stressed control group, respectively; ^^ and ^^^ represent p < 0.01 and p < 0.001 v.s. the Non-treatment stressed group, respectively.
    Figure Legend Snippet: The effects of EE and RJ treatment on the hippocampal BDNF expression. The BDNF levels in the stressed group were significantly decreased than in the control group. EE and RJ treatment increased BDNF levels in the stressed rats. *, **, and *** represent p < 0.05, p < 0.01, and p < 0.001 v.s. the Non-stressed control group, respectively; ^^ and ^^^ represent p < 0.01 and p < 0.001 v.s. the Non-treatment stressed group, respectively.

    Techniques Used: Expressing, Control

    Related Articles

    Enzyme-linked Immunosorbent Assay:

    Article Title: Effects of prolonged abstinence from METH on the hippocampal BDNF levels, neuronal numbers and apoptosis in methamphetamine-sensitized rats.
    Article Snippet: Methamphetamine (METH) use is associated with neuronal damage in various regions of brain, while effects of prolonged abstinence on METH-induced damage are not quite clear.. This study evaluated serum and hippocampal BDNF levels, neuronal numbers and apoptosis in METH-sensitized and abstinent rats.. Rats were sensitized to METH (2 mg/kg, daily/18 days, s.c.).

    Article Title: Effects of BDNF receptor antagonist on the severity of physical and psychological dependence, morphine-induced locomotor sensitization and the ventral tegmental area-nucleus accumbens BDNF levels in morphine- dependent and withdrawn rats.
    Article Snippet: This study examined the effects of systemic administration of the TrkB receptor antagonist (ANA-12) on the severity of physical and psychological dependence and morphine-induced locomotor sensitization, the ventral tegmental area (VTA)-nucleus accumbens (NAc) BDNF levels in morphine-dependent and withdrawn rats.. Rats were injected with bi-daily doses (10 mg/kg, at 12h intervals) of morphine for 10 days.. Then, rats were tested for naloxoneprecipitated morphine withdrawal signs, the anxiety (the elevated plus maze-EPM) after the last morphine injection and injection of ANA12 (ip).

    Article Title: Effects of maternal hypothyroidism during pregnancy on learning, memory and hippocampal BDNF in rat pups: Beneficial effects of exercise.
    Article Snippet: 55 Abstract—Hypothyroidism during early development leads to numerous morphological, biochemical and functional changes in developing brain.. In this study, we investigated the effects of voluntary and treadmill exercise on learning, memory and hippocampal BDNF levels in both hypothyroid male and female rat pups.. To induce hypothyroidism in the mothers, 6-propyl-2-thiouracil (PTU) was added to their drinking water (100 mg/L) from their embryonic day 6 to their postnatal day (PND) 21.

    Article Title: Effect of crocin on morphine tolerance and serum BDNF levels in a rat model of neuropathic pain.
    Article Snippet: Background Chronic use of morphine treatment for neuropathic pain leads to morphine-induced analgesic tolerance.. Crocin contained in Crocus sativus L., exerts anti‐inflammatory and analgesic effects.. This study examined the effects of crocin on morphine tolerance and serum BDNF levels on neuropathic pain induced by chronic constriction injury (CCI) in rats.

    Article Title: Pre-treatment with royal jelly, environmental enrichment, and their combination role in stress induced neurobehavioral deficits in male rats
    Article Snippet: .. The evaluation of serum corticosterone levels and hippocampal BDNF levels was conducted using an enzyme-linked immunosorbent assay (ELISA) with a commercially available ELISA kit (E20160505043, Hangzhou Eastbiopharm Co. Ltd., Zhejiang Province, China) and rat BDNF ELISA kits from Boster Biological Technology Co. with a sensitivity limit of 4 pg/ml following the instructions provided by the manufacturer. .. All measurements were performed at room temperature based on Biolegend instructions using microplate reader with 450 nm filter.

    Article Title: Microinjection of the BDNF receptor antagonist ANA-12 into the nucleus accumbens and medial-prefrontal cortex attenuates morphine-induced reward memory, and alterations of BDNF levels and apoptotic cells in rats.
    Article Snippet: This study was designed to examine the effects of intranucleus accumbens (NAc) of BDNF receptor antagonist ANA-12 on the acquisition and expression and intramedial-prefrontal cortex (mPFC) of ANA-12 on the extinction and reinstatement of morphine-induced conditioned place preference (CPP) and also BDNF levels and apoptotic neurons in the NAc and mPFC of rats.. In this study, adult male Wistar rats (200–250 g) were used.. Two separate cannulas were inserted bilaterally into the NAc and/or mPFC.

    Article Title: Effects of moderate treadmill exercise and fluoxetine on behavioural and cognitive deficits, hypothalamic-pituitary-adrenal axis dysfunction and alternations in hippocampal BDNF and mRNA expression of apoptosis - related proteins in a rat model of post-traumatic stress disorder.
    Article Snippet: Please cite this article as: Shafia, S., Vafaei, A.A., Samaei, S.A., Bandegi, A.R., Rafiei, A., Valadan, R., HosseiniKhah, Z., Mohammadkhani, R., Rashidy-Pour, A., Effects of moderate treadmill exercise and fluoxetine on behavioural and cognitive deficits, hypothalamic-pituitary-adrenal axis dysfunction and alternations in hippocampal BDNF and mRNA expression of apoptosis – related proteins in a rat model of post-traumatic stress disorder, Neurobiology of Learning and Memory (2017), doi: http://dx.doi.org/10.1016/j.nlm.2017.01.009



    Similar Products

    93
    Boster Bio rat bdnf elisa kits
    Experimental Timeline: Rats were treated with EE, RJ, and EE + RJ for 14 consecutive days. Stress was induced on days 8–14. Behavioral tests were conducted on days 15–18. On day 19, the animals were decapitated to assess serum corticosterone and hippocampal <t>BDNF</t> levels.
    Rat Bdnf Elisa Kits, supplied by Boster Bio, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rat+bdnf+elisa+kits/Rat+BDNF+ELISA+Kit+EZ-Set/pmc13092850-95-33-38
    Average 93 stars, based on 1 article reviews
    rat bdnf elisa kits - by Bioz Stars, 2026-09
    93/100 stars
      Buy from Supplier

    94
    Guangzhou JET Bio-Filtration rat bdnf (brain derived neurotrophic factor) elisa kit
    Experimental Timeline: Rats were treated with EE, RJ, and EE + RJ for 14 consecutive days. Stress was induced on days 8–14. Behavioral tests were conducted on days 15–18. On day 19, the animals were decapitated to assess serum corticosterone and hippocampal <t>BDNF</t> levels.
    Rat Bdnf (Brain Derived Neurotrophic Factor) Elisa Kit, supplied by Guangzhou JET Bio-Filtration, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rat+bdnf+elisa+kits/Rat+BDNF+(Brain+Derived+Neurotrophic+Factor)+ELISA+Kit/custom%40e-el-r1235%4010%2E1177%2F1096620x261448411
    Average 94 stars, based on 1 article reviews
    rat bdnf (brain derived neurotrophic factor) elisa kit - by Bioz Stars, 2026-09
    94/100 stars
      Buy from Supplier

    95
    Elabscience Biotechnology rat bdnf elisa kit
    Persistent hyperalgesia in the RPP model (A and B) Paw withdrawal latency (A) and 50% paw withdrawal threshold (B) of each rat ( n = 3–6). (C) Representative histological images of DRG from T10-S4 by H&E staining. Arrow, Schwann cell; ∗, nuclei; #, cytoplasm. Scale bars, 50 μm and 25 μm. (D and E) Representative IHC images (D) and quantification (E) of <t>BDNF</t> in the DRG from T10-S4. Brown DAB staining indicates BDNF immunopositivity. The staining intensity was semi-quantitatively scored as follows: (1) weak, (2) moderate, and (3) intense. Scale bars, 50 μm. ( n = 3 biological replicates per group). (F) Serum BDNF level on days 12 and 24 of RPP modeling ( n = 3). Data are presented as the mean ± SD; ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, two-way ANOVA (A and B) or one-way ANOVA (E and F).
    Rat Bdnf Elisa Kit, supplied by Elabscience Biotechnology, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rat+bdnf+elisa+kits/Rat+BDNF+(Brain+Derived+Neurotrophic+Factor)+ELISA+Kit/pmc13015246-16-0-5
    Average 95 stars, based on 1 article reviews
    rat bdnf elisa kit - by Bioz Stars, 2026-09
    95/100 stars
      Buy from Supplier

    95
    Elabscience Biotechnology e el r1235
    Persistent hyperalgesia in the RPP model (A and B) Paw withdrawal latency (A) and 50% paw withdrawal threshold (B) of each rat ( n = 3–6). (C) Representative histological images of DRG from T10-S4 by H&E staining. Arrow, Schwann cell; ∗, nuclei; #, cytoplasm. Scale bars, 50 μm and 25 μm. (D and E) Representative IHC images (D) and quantification (E) of <t>BDNF</t> in the DRG from T10-S4. Brown DAB staining indicates BDNF immunopositivity. The staining intensity was semi-quantitatively scored as follows: (1) weak, (2) moderate, and (3) intense. Scale bars, 50 μm. ( n = 3 biological replicates per group). (F) Serum BDNF level on days 12 and 24 of RPP modeling ( n = 3). Data are presented as the mean ± SD; ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, two-way ANOVA (A and B) or one-way ANOVA (E and F).
    E El R1235, supplied by Elabscience Biotechnology, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rat+bdnf+elisa+kits/Rat+BDNF+(Brain+Derived+Neurotrophic+Factor)+ELISA+Kit/pmc13015246-16-8-5
    Average 95 stars, based on 1 article reviews
    e el r1235 - by Bioz Stars, 2026-09
    95/100 stars
      Buy from Supplier

    94
    Guangzhou JET Bio-Filtration pgd2 (prostaglandin d2) elisa kit
    Persistent hyperalgesia in the RPP model (A and B) Paw withdrawal latency (A) and 50% paw withdrawal threshold (B) of each rat ( n = 3–6). (C) Representative histological images of DRG from T10-S4 by H&E staining. Arrow, Schwann cell; ∗, nuclei; #, cytoplasm. Scale bars, 50 μm and 25 μm. (D and E) Representative IHC images (D) and quantification (E) of <t>BDNF</t> in the DRG from T10-S4. Brown DAB staining indicates BDNF immunopositivity. The staining intensity was semi-quantitatively scored as follows: (1) weak, (2) moderate, and (3) intense. Scale bars, 50 μm. ( n = 3 biological replicates per group). (F) Serum BDNF level on days 12 and 24 of RPP modeling ( n = 3). Data are presented as the mean ± SD; ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, two-way ANOVA (A and B) or one-way ANOVA (E and F).
    Pgd2 (Prostaglandin D2) Elisa Kit, supplied by Guangzhou JET Bio-Filtration, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rat+bdnf+elisa+kits/PGD2+(Prostaglandin+D2)+ELISA+Kit/custom%40e-el-0066%4041968960
    Average 94 stars, based on 1 article reviews
    pgd2 (prostaglandin d2) elisa kit - by Bioz Stars, 2026-09
    94/100 stars
      Buy from Supplier

    94
    Guangzhou JET Bio-Filtration mouse fe (ferritin) elisa kit
    Persistent hyperalgesia in the RPP model (A and B) Paw withdrawal latency (A) and 50% paw withdrawal threshold (B) of each rat ( n = 3–6). (C) Representative histological images of DRG from T10-S4 by H&E staining. Arrow, Schwann cell; ∗, nuclei; #, cytoplasm. Scale bars, 50 μm and 25 μm. (D and E) Representative IHC images (D) and quantification (E) of <t>BDNF</t> in the DRG from T10-S4. Brown DAB staining indicates BDNF immunopositivity. The staining intensity was semi-quantitatively scored as follows: (1) weak, (2) moderate, and (3) intense. Scale bars, 50 μm. ( n = 3 biological replicates per group). (F) Serum BDNF level on days 12 and 24 of RPP modeling ( n = 3). Data are presented as the mean ± SD; ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, two-way ANOVA (A and B) or one-way ANOVA (E and F).
    Mouse Fe (Ferritin) Elisa Kit, supplied by Guangzhou JET Bio-Filtration, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rat+bdnf+elisa+kits/Mouse+FE+(Ferritin)+ELISA+Kit/custom%40e-el-m0491%4041966311
    Average 94 stars, based on 1 article reviews
    mouse fe (ferritin) elisa kit - by Bioz Stars, 2026-09
    94/100 stars
      Buy from Supplier

    94
    Guangzhou JET Bio-Filtration mouse il-10 (interleukin 10) elisa kit
    Persistent hyperalgesia in the RPP model (A and B) Paw withdrawal latency (A) and 50% paw withdrawal threshold (B) of each rat ( n = 3–6). (C) Representative histological images of DRG from T10-S4 by H&E staining. Arrow, Schwann cell; ∗, nuclei; #, cytoplasm. Scale bars, 50 μm and 25 μm. (D and E) Representative IHC images (D) and quantification (E) of <t>BDNF</t> in the DRG from T10-S4. Brown DAB staining indicates BDNF immunopositivity. The staining intensity was semi-quantitatively scored as follows: (1) weak, (2) moderate, and (3) intense. Scale bars, 50 μm. ( n = 3 biological replicates per group). (F) Serum BDNF level on days 12 and 24 of RPP modeling ( n = 3). Data are presented as the mean ± SD; ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, two-way ANOVA (A and B) or one-way ANOVA (E and F).
    Mouse Il 10 (Interleukin 10) Elisa Kit, supplied by Guangzhou JET Bio-Filtration, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rat+bdnf+elisa+kits/Mouse+IL-10+(Interleukin+10)+ELISA+Kit/custom%40e-el-m0046%4041952146
    Average 94 stars, based on 1 article reviews
    mouse il-10 (interleukin 10) elisa kit - by Bioz Stars, 2026-09
    94/100 stars
      Buy from Supplier

    94
    Guangzhou JET Bio-Filtration mouse tnf-α (tumor necrosis factor alpha) elisa kit
    Persistent hyperalgesia in the RPP model (A and B) Paw withdrawal latency (A) and 50% paw withdrawal threshold (B) of each rat ( n = 3–6). (C) Representative histological images of DRG from T10-S4 by H&E staining. Arrow, Schwann cell; ∗, nuclei; #, cytoplasm. Scale bars, 50 μm and 25 μm. (D and E) Representative IHC images (D) and quantification (E) of <t>BDNF</t> in the DRG from T10-S4. Brown DAB staining indicates BDNF immunopositivity. The staining intensity was semi-quantitatively scored as follows: (1) weak, (2) moderate, and (3) intense. Scale bars, 50 μm. ( n = 3 biological replicates per group). (F) Serum BDNF level on days 12 and 24 of RPP modeling ( n = 3). Data are presented as the mean ± SD; ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, two-way ANOVA (A and B) or one-way ANOVA (E and F).
    Mouse Tnf α (Tumor Necrosis Factor Alpha) Elisa Kit, supplied by Guangzhou JET Bio-Filtration, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rat+bdnf+elisa+kits/Mouse+TNF-%CE%B1+(Tumor+Necrosis+Factor+Alpha)+ELISA+Kit/custom%40e-el-m3063%4041966320
    Average 94 stars, based on 1 article reviews
    mouse tnf-α (tumor necrosis factor alpha) elisa kit - by Bioz Stars, 2026-09
    94/100 stars
      Buy from Supplier

    94
    Guangzhou JET Bio-Filtration mini sample mouse il-1β (interleukin 1 beta) elisa kit
    Persistent hyperalgesia in the RPP model (A and B) Paw withdrawal latency (A) and 50% paw withdrawal threshold (B) of each rat ( n = 3–6). (C) Representative histological images of DRG from T10-S4 by H&E staining. Arrow, Schwann cell; ∗, nuclei; #, cytoplasm. Scale bars, 50 μm and 25 μm. (D and E) Representative IHC images (D) and quantification (E) of <t>BDNF</t> in the DRG from T10-S4. Brown DAB staining indicates BDNF immunopositivity. The staining intensity was semi-quantitatively scored as follows: (1) weak, (2) moderate, and (3) intense. Scale bars, 50 μm. ( n = 3 biological replicates per group). (F) Serum BDNF level on days 12 and 24 of RPP modeling ( n = 3). Data are presented as the mean ± SD; ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, two-way ANOVA (A and B) or one-way ANOVA (E and F).
    Mini Sample Mouse Il 1β (Interleukin 1 Beta) Elisa Kit, supplied by Guangzhou JET Bio-Filtration, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rat+bdnf+elisa+kits/Mini+Sample+Mouse+IL-1%CE%B2+(Interleukin+1+Beta)+ELISA+Kit/custom%40e-msel-m0003%4041955700
    Average 94 stars, based on 1 article reviews
    mini sample mouse il-1β (interleukin 1 beta) elisa kit - by Bioz Stars, 2026-09
    94/100 stars
      Buy from Supplier

    94
    Guangzhou JET Bio-Filtration human cortisol elisa kit
    Persistent hyperalgesia in the RPP model (A and B) Paw withdrawal latency (A) and 50% paw withdrawal threshold (B) of each rat ( n = 3–6). (C) Representative histological images of DRG from T10-S4 by H&E staining. Arrow, Schwann cell; ∗, nuclei; #, cytoplasm. Scale bars, 50 μm and 25 μm. (D and E) Representative IHC images (D) and quantification (E) of <t>BDNF</t> in the DRG from T10-S4. Brown DAB staining indicates BDNF immunopositivity. The staining intensity was semi-quantitatively scored as follows: (1) weak, (2) moderate, and (3) intense. Scale bars, 50 μm. ( n = 3 biological replicates per group). (F) Serum BDNF level on days 12 and 24 of RPP modeling ( n = 3). Data are presented as the mean ± SD; ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, two-way ANOVA (A and B) or one-way ANOVA (E and F).
    Human Cortisol Elisa Kit, supplied by Guangzhou JET Bio-Filtration, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rat+bdnf+elisa+kits/Human+Cortisol+ELISA+Kit/custom%40e-el-0157%4041967319
    Average 94 stars, based on 1 article reviews
    human cortisol elisa kit - by Bioz Stars, 2026-09
    94/100 stars
      Buy from Supplier

    Image Search Results


    Experimental Timeline: Rats were treated with EE, RJ, and EE + RJ for 14 consecutive days. Stress was induced on days 8–14. Behavioral tests were conducted on days 15–18. On day 19, the animals were decapitated to assess serum corticosterone and hippocampal BDNF levels.

    Journal: IBRO Neuroscience Reports

    Article Title: Pre-treatment with royal jelly, environmental enrichment, and their combination role in stress induced neurobehavioral deficits in male rats

    doi: 10.1016/j.ibneur.2026.03.012

    Figure Lengend Snippet: Experimental Timeline: Rats were treated with EE, RJ, and EE + RJ for 14 consecutive days. Stress was induced on days 8–14. Behavioral tests were conducted on days 15–18. On day 19, the animals were decapitated to assess serum corticosterone and hippocampal BDNF levels.

    Article Snippet: The evaluation of serum corticosterone levels and hippocampal BDNF levels was conducted using an enzyme-linked immunosorbent assay (ELISA) with a commercially available ELISA kit (E20160505043, Hangzhou Eastbiopharm Co. Ltd., Zhejiang Province, China) and rat BDNF ELISA kits from Boster Biological Technology Co. with a sensitivity limit of 4 pg/ml following the instructions provided by the manufacturer.

    Techniques:

    The effects of EE and RJ treatment on the hippocampal BDNF expression. The BDNF levels in the stressed group were significantly decreased than in the control group. EE and RJ treatment increased BDNF levels in the stressed rats. *, **, and *** represent p < 0.05, p < 0.01, and p < 0.001 v.s. the Non-stressed control group, respectively; ^^ and ^^^ represent p < 0.01 and p < 0.001 v.s. the Non-treatment stressed group, respectively.

    Journal: IBRO Neuroscience Reports

    Article Title: Pre-treatment with royal jelly, environmental enrichment, and their combination role in stress induced neurobehavioral deficits in male rats

    doi: 10.1016/j.ibneur.2026.03.012

    Figure Lengend Snippet: The effects of EE and RJ treatment on the hippocampal BDNF expression. The BDNF levels in the stressed group were significantly decreased than in the control group. EE and RJ treatment increased BDNF levels in the stressed rats. *, **, and *** represent p < 0.05, p < 0.01, and p < 0.001 v.s. the Non-stressed control group, respectively; ^^ and ^^^ represent p < 0.01 and p < 0.001 v.s. the Non-treatment stressed group, respectively.

    Article Snippet: The evaluation of serum corticosterone levels and hippocampal BDNF levels was conducted using an enzyme-linked immunosorbent assay (ELISA) with a commercially available ELISA kit (E20160505043, Hangzhou Eastbiopharm Co. Ltd., Zhejiang Province, China) and rat BDNF ELISA kits from Boster Biological Technology Co. with a sensitivity limit of 4 pg/ml following the instructions provided by the manufacturer.

    Techniques: Expressing, Control

    Persistent hyperalgesia in the RPP model (A and B) Paw withdrawal latency (A) and 50% paw withdrawal threshold (B) of each rat ( n = 3–6). (C) Representative histological images of DRG from T10-S4 by H&E staining. Arrow, Schwann cell; ∗, nuclei; #, cytoplasm. Scale bars, 50 μm and 25 μm. (D and E) Representative IHC images (D) and quantification (E) of BDNF in the DRG from T10-S4. Brown DAB staining indicates BDNF immunopositivity. The staining intensity was semi-quantitatively scored as follows: (1) weak, (2) moderate, and (3) intense. Scale bars, 50 μm. ( n = 3 biological replicates per group). (F) Serum BDNF level on days 12 and 24 of RPP modeling ( n = 3). Data are presented as the mean ± SD; ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, two-way ANOVA (A and B) or one-way ANOVA (E and F).

    Journal: iScience

    Article Title: A pharmacological rat model of recurrent pelvic pain exhibiting hyperalgesia and depression-like behaviors

    doi: 10.1016/j.isci.2026.115059

    Figure Lengend Snippet: Persistent hyperalgesia in the RPP model (A and B) Paw withdrawal latency (A) and 50% paw withdrawal threshold (B) of each rat ( n = 3–6). (C) Representative histological images of DRG from T10-S4 by H&E staining. Arrow, Schwann cell; ∗, nuclei; #, cytoplasm. Scale bars, 50 μm and 25 μm. (D and E) Representative IHC images (D) and quantification (E) of BDNF in the DRG from T10-S4. Brown DAB staining indicates BDNF immunopositivity. The staining intensity was semi-quantitatively scored as follows: (1) weak, (2) moderate, and (3) intense. Scale bars, 50 μm. ( n = 3 biological replicates per group). (F) Serum BDNF level on days 12 and 24 of RPP modeling ( n = 3). Data are presented as the mean ± SD; ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, two-way ANOVA (A and B) or one-way ANOVA (E and F).

    Article Snippet: Rat BDNF ELISA Kit , Elabscience , Cat# E-EL-R1235.

    Techniques: Staining

    Comorbid depression-like behavior in the RPP model (A and B) Serum BDNF (A) and 5-HT (B) levels in the RPP model ( n = 6). (C and D) Sucrose preference ratio (C) and immobility time (D) in the RPP model ( n = 8). Data are presented as the mean ± SD; ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, paired t test (A and B) or two-way ANOVA (C and D).

    Journal: iScience

    Article Title: A pharmacological rat model of recurrent pelvic pain exhibiting hyperalgesia and depression-like behaviors

    doi: 10.1016/j.isci.2026.115059

    Figure Lengend Snippet: Comorbid depression-like behavior in the RPP model (A and B) Serum BDNF (A) and 5-HT (B) levels in the RPP model ( n = 6). (C and D) Sucrose preference ratio (C) and immobility time (D) in the RPP model ( n = 8). Data are presented as the mean ± SD; ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p < 0.001, paired t test (A and B) or two-way ANOVA (C and D).

    Article Snippet: Rat BDNF ELISA Kit , Elabscience , Cat# E-EL-R1235.

    Techniques: